Biomarker Test Summary
| Test | Technology | Result Interpretation | CPT Codes | Method | Targeted Therapies |
|---|---|---|---|---|---|
| ALK | Fish | Translocation | 88377 | CTC | Xalkori©, Zykadia©, Alecensa© |
| AR | Expression | Expression | 88346 or 88350 | CTC | Zytiga©, Xtandi© |
| BRAF | Sequencing | Mutation | 81210 | ctDNA | Zelboraf©, Tafinlar© |
| CTC | Antibody Capture | Enumeration | 86152/86153 88346x1, 88350x2 | CTC | |
| EGFR T790M,DEL19,L858R | Sequencing | Mutation | 81235 | ctDNA | Tarceva©, Gilotrif©, Iressa©, Tagrisso© |
| ER | Expression | Expression | 88346 or 88350 | CTC | Nolvadex©, Aromatase Inhibitors |
| FGFR1 | FISH | Amplication | 88377 | CTC | Nolvadex©, Faslodex©, Femara©, Arimidex©, Aromasin© |
| HER2 | FISH | Amplification | 88377 | CTC | Herceptin©, Perjeta© |
| KRAS | Sequencing | Mutation | 81275 | ctDNA | Erbitux©, Vectibix© |
| MET | FISH | Amplification | 88377 | CTC | Xalkori©, Cabometyx©, Exelixi©, Tivantinib© |
| PD-L1 | Expression | Expression | 88346 or 88350 | CTC | Keytruda©, Opdivo© |
| PR | Expression | Expression | 88346 or 88350 | CTC | Nolvadex©, Aromatase Inhibitors |
| RET | FISH | Translocation | 88377 | CTC | Cabometyx©, Capresla© |
| ROS1 | FISH | Translocation | 88377 | CTC | Xalkori©, Zykadia©, Alecensa© |